Scottish Medicines Consortium Recommends Versatis(R) In Post-Herpetic Neuralgia Part 2

Presentation: Versatis be a medicated plaster (10cm x 14cm) encompass 700 mg (5% w/w) of lidocaine contained with an aqueous sticky pack starting pop. Indication: Treatment of neuropathic niggle associated effective supreme recent herpes zoster contamination (post-herpetic neuralgia, PHN). Dosage and manoeuvre of direction: Adults and elderly patients: Use practised of three plasters all for conscious to 12 hours, hound by at smallest a 12 hour plaster-free lull. Cover aching borough once by the side of a daily basis. Apply the plaster to intact, scorch, non-irritated wrapping (after fortifying of the shingles). Remove hair in pretentious area with scissors (do not shave). Remove the plaster from sachet and its perceived liner until that time apply head-on to the skin. Plasters may be cut backbone to proportions. Patients make self-conscious than 18 years: Not recommended. Contra-indications: Hypersensitivity to involved loose ends, any excipients, or regional anaesthetics of amide manner (e.g. bupivacaine, etidocaine, mepivacaine and prilocaine). Warnings and precautions: Do not apply to inflamed or spoilt skin (e.g. active herpes zoster lesion, atopic dermatitis or wounds), mucous membranes or the eye. Plasters contain propylene glycol which may upshot in skin irritant, methyl parahydroxybenzoate and propyl parahydroxybenzoate which may cause allergic sensitivity. Use with alertness in patients with authoritarian cardiac impairment, severe renal impairment or severe hepatic impairment. Interactions: No clinically of a petty something interactions enjoy be observed in clinical study. Absorption of lidocaine from the skin is fur. Use with caution in patients delivery Class I antiarrhythmic drugs (e.g. tocainide, mexiletine) or other local anaesthetics.

Pregnancy and lactation: Do not sear up during pregnancy or breast-feeding. Undesirable effects: Very undisputed (³10%): administration break camp reactions (e.g. erythema, unwary, pruritus, burning). Uncommon (>0.1%-£1%): skin blister, skin lesion. Very sporadic (<0.01%) but potentially essential: anaphylaxis, hypersensitivity. Adverse reactions be predominantly of soft and relax severity. Systemic adverse reactions be unbelievable. See SPC for meticulous register. Overdose: Unlikely. If suspected, cut out plasters, bring supportive remedy (see SPC).

Legal taxonomy: POM. Marketing Authorisation numeral, pack size and unembellished NHS cut: PL 21727/0016, 30 plasters (£ 72.40). Marketing Authorisation Holder: Grünenthal Ltd, Regus Lakeside House, 1 Furzeground Way, Stockley Park East, Uxbridge, Middlesex, UB11 1BD, UK. Date of file: June 2008. V0138 Information in the order of adverse point broadsheet journalism can be found at: Grunenthal Ltd

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